Two Color, Two Fusion Translocation Probe

Ref: 16-010

The IGH/MAF DNA-FISH Probe is designed to detect the translocation between the IGH gene located on 14q32 and the MAF gene located on 16q23 by fluorescence in situ hybridization (FISH).[1]  The translocation between the IGH and MAF gene, designated as t(14;16)(q32;q23), is found in 2-10% of multiple myeloma (MM) cases and is associated with a more aggressive disease along with an unfavorable prognosis and outcome.[2,3]

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<em>IGH</em>/<em>MAF</em> DNA Probes